Advancing Basic Science for Humanity
Mutations of the TRIO gene are found in a significant number of people suffering from several neurodevelopmental disorders.
Small clusters of brain cells grown from stem cells in a laboratory dish mimic the development and organization of full-size chimpanzee brains.
Columbia team harnesses powerful technology to uncover never-before-seen details of the nervous system, demonstrating SCAPE’s broad potential to decipher the brain.
Researchers describe neural mechanisms responsible for the organisms' strategic local search for food.
In an effort to improve robotic swarming algorithms, an interdisciplinary team of scientists will study how the brain allows an animal to navigate and change its route while moving.
Salk scientists compare the development of brain cells between humans and nonhuman primates in a novel way.
A new Johns Hopkins study found that rats' ability to recalibrate these learned relationships is ever-evolving, moment-by-moment.
Salk study is the first to directly examine cells from patients whose depression doesn’t respond to SSRIs.
Columbia-led discovery in mice aids efforts to map the circuitry of the brain’s learning center; stands to inform studies of psychiatric disorders in which this circuitry goes awry.
In rat models, the novel scaffolding mimicked natural anatomy and boosted stem cell-based treatment; the approach is scalable to humans and advances effort toward clinical trials.